Journal article
Pharmacological evidence of medicinal cannabis in oncology: a systematic review
Supportive care in cancer, Vol.27, pp.3195-3207
01/09/2019
PMID: 31062109
Metrics
6 Record Views
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites
Abstract
Purpose
This systematic literature review examines research into the use of medicinal cannabis in cancer management. The aim was to identify the gaps in knowledge on the dose, dosing schedule and absorption of the administration routes of medicinal cannabis use in oncology.
Methods
A comprehensive search of the literature was conducted across six databases to identify original data reporting the pharmacology of medicinal cannabis in oncology.
Results
Eighteen articles were selected for review. Of the selected articles, ten were identified as randomised control trials, two experimental studies, two retrospective cohort studies and four case studies. Four articles reported absorption data and one drug interaction study was identified.
Conclusions
There is little evidence reported in the literature on the absorption of medicinal cannabis in cancer populations. Various reasons are explored for the lack of pharmacokinetic studies for medicinal cannabis in cancer populations, including the availability of assays to accurately assess cannabinoid levels, lack of clinical biomarkers and patient enrolment for pharmacokinetic studies.
Details
- Title
- Pharmacological evidence of medicinal cannabis in oncology: a systematic review
- Creators
- Danielle Brown - Endeavour College of Natural HealthMichael Watson - Endeavour College of Natural HealthJanet Schloss - Endeavour College of Natural Health
- Publication Details
- Supportive care in cancer, Vol.27, pp.3195-3207
- Publisher
- Springer Nature
- Number of pages
- 13
- Grant note
- FIT-BioCeuticals Ltd. Endeavour College of Natural Health, Australia
- Identifiers
- 991013104212802368
- Copyright
- (c) Springer-Verlag GmbH Germany, part of Springer Nature 2019.
- Academic Unit
- National Centre for Naturopathic Medicine
- Language
- English
- Resource Type
- Journal article