Book chapter
A method for discovery of genome-wide SNP between any two genotypes from whole-genome re-sequencing data
Methods in Molecular Biology, Vol.1099, pp.287-294
Humana Press
2014
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Source: InCites
Abstract
<p>Advances in sequencing technologies have aided the discovery of millions of genome-wide DNA polymorphisms such as single-nucleotide polymorphisms (<a href="http://link.springer.com/search?dc.title=SNPs&facet-content-type=ReferenceWorkEntry&sortOrder=relevance">SNPs</a>) and insertion–deletions (InDels) which are an invaluable resource for marker-assisted breeding. Presently available bioinformatics tools assist the discovery of polymorphisms between target genotypes and the reference genome for a range of species. The discovery of polymorphisms between two genotypes within a breeding program is complicated by several factors such as bias in the number of reads from each genotype and residual heterozygosity within each genotype. In this chapter, we describe a novel approach where polymorphisms between a pair of genotypes are discovered from whole-genome re-sequencing data.</p>
Details
- Title
- A method for discovery of genome-wide SNP between any two genotypes from whole-genome re-sequencing data
- Creators
- S Gopala Krishnan - Indian Agricultural Research InstituteDaniel LE Waters - Southern Cross UniversityRobert J Henry - University of Queensland
- Contributors
- John M Walker (Editor of compilation)Agnelo Furtado (Editor of compilation)Robert J Henry (Editor of compilation)
- Publication Details
- Methods in Molecular Biology, Vol.1099, pp.287-294
- Publisher
- Humana Press; New York
- Identifiers
- 1783; 991012820526902368
- Academic Unit
- Southern Cross Plant Science
- Resource Type
- Book chapter