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Trimethoprim-sulfonamide: a valid antimicrobial treatment in foals?
Journal article   Open access   Peer reviewed

Trimethoprim-sulfonamide: a valid antimicrobial treatment in foals?

Kajsa Gustafsson, Benjamin W Sykes, Denis Verwilghen, Katrien Palmers, Stacey Sullivan and Gaby van Galen
Journal of the American Veterinary Medical Association, Vol.262(6)
06/2024
PMID: 38479105
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Published (Version of record)CC BY-NC V4.0 Open Access
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Published (Version of record)CC BY-NC V4.0 Open

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Abstract

antimicrobial treatment sulfonamides foal trimethoprim
Trimethoprim-sulfonamide (TMPS) combinations are widely used to treat a range of infectious diseases in horses, but some equine practitioners are reluctant to use them for treatment of both neonatal and older foals. Considering the emergence of increased antimicrobial resistance, the use of protected antimicrobials commonly prescribed to foals should be avoided and alternative first-line therapy considered, where appropriate. This review examines the characteristics and pharmacokinetics of TMPS and its suitability for treatment of foals. Data regarding dosage and route of administration are reported on the basis of recent publications in foals. The review intends to share significant information about the common infections that are most likely responsive to TMPS treatment in foals and, as such, where TMPS might be considered a suitable first-line therapeutic option.

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