Journal article
Toward a Universal Unit for Quantification of Antibiotic Resistance Genes in Environmental Samples
Environmental Science & Technology, Vol.57(26), pp.9713-9721
13/06/2023
PMID: 37310875
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Source: InCites
Abstract
Surveillance of antibiotic resistance genes (ARGs) has been increasingly conducted in environmental sectors to complement the surveys in human and animal sectors under the “One-Health” framework. However, there are substantial challenges in comparing and synthesizing the results of multiple studies that employ different test methods and approaches in bioinformatic analysis. In this article, we consider the commonly used quantification units (ARG copy per cell, ARG copy per genome, ARG density, ARG copy per 16S rRNA gene, RPKM, coverage, PPM, etc.) for profiling ARGs and suggest a universal unit (ARG copy per cell) for reporting such biological measurements of samples and improving the comparability of different surveillance efforts.
Details
- Title
- Toward a Universal Unit for Quantification of Antibiotic Resistance Genes in Environmental Samples
- Creators
- Xiaole Yin - University of Hong KongXi Chen - University of Hong KongXiao-Tao Jiang - University of New South WalesYing Yang - Sun Yat-sen UniversityBing Li - Tsinghua UniversityMarcus Ho-Hin Shum - University of Hong KongTommy T. Y. Lam - University of Hong KongGabriel M. Leung - Hong Kong Science and Technology Parks CorporationJoan Rose - Michigan State UniversityConcepcion Sanchez-Cid - Université Claude Bernard Lyon 1Timothy M. Vogel - Université Claude Bernard Lyon 1Fiona Walsh - Maynooth University (Kildare, Ireland)Thomas U. Berendonk - Dresden University of TechnologyJanet Midega - Wellcome TrustChibuzor Uchea - Wellcome TrustDominic Frigon - McGill UniversityGerard D. Wright - McMaster UniversityCarlos Bezuidenhout - North-West UniversityRenata C. Picão - Universidade Federal do Rio de JaneiroShaikh Z. Ahammad - Indian Institute of Technology DelhiPer Halkjær Nielsen - Aalborg UniversityPhilip Hugenholtz - The University of QueenslandNicholas J. Ashbolt - Southern Cross UniversityGianluca Corno - Water Research InstituteDespo Fatta-Kassinos - University of CyprusHelmut Bürgmann - Swiss Federal Institute of Aquatic Science and TechnologyHeike Schmitt - National Institute for Public Health and the EnvironmentChang-Jun Cha - Chung-Ang UniversityAmy Pruden - Virginia TechKornelia Smalla - Institute for Epidemiology and Pathogen Diagnostics (Braunschweig, Germany)Eddie Cytryn - Ministry of Agriculture and Rural Development (Israel)Yu Zhang - Chinese Academy of SciencesMin Yang - Chinese Academy of SciencesYong-Guan Zhu - Chinese Academy of SciencesArnaud Dechesne - Technical University of DenmarkBarth F. Smets - Technical University of DenmarkDavid W. Graham - Newcastle UniversityMichael R. Gillings - Macquarie UniversityWilliam H. Gaze - University of ExeterCélia M. Manaia - Universidade Católica PortuguesaMark C. M. van Loosdrecht - Delft University of TechnologyPedro J. J. Alvarez - Rice UniversityMartin J. Blaser - Rutgers University (Piscataway, USA)James M. Tiedje - Michigan State UniversityEdward Topp - London Research and Development Centre (LRDC)Tong Zhang - University of Hong Kong
- Publication Details
- Environmental Science & Technology, Vol.57(26), pp.9713-9721
- Comment
- doi: 10.1021/acs.est.3c00159
- Publisher
- American Chemical Society
- Identifiers
- 991013124213702368
- Copyright
- © 2023 American Chemical Society.
- Academic Unit
- Faculty of Science and Engineering
- Language
- English
- Resource Type
- Journal article