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Journal article
Time to Hang Up the Gloves: A Scoping Review of Evidence on Non-Sterile Glove Use During Intravenous Antimicrobial Preparation and Administration
Journal of advanced nursing, Vol.First online
25/09/2025
PMID: 40999763
Appears in Recent Faculty of Health Publications
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Abstract
Aims: To systematically summarise evidence related to the use of non-sterile gloves when preparing and administering intravenous antimicrobials.
Design: Scoping review.
Methods: A rigorous scoping review was undertaken following Arksey and O'Malley's (2005) framework and the modified Preferred Reporting Items for Systematic Reviews and Meta-analyses extension for scoping review guidelines (2018). Five databases and grey literature were included in the search. Literature published between 2009 and 2024 was included.
Data Sources: Five databases (Medline, CINAHL, EMBASE, Scopus and Web of Science) and the grey literature were searched in February 2024.
Results: Three studies were included; however, none directly addressed correct non-sterile glove use during intravenous antimicrobial preparation or administration in clinical practice.
Conclusion: We found no evidence to support the use of non-sterile gloves in intravenous antimicrobial preparation. There is an urgent need for rigorous research to inform the development of clear guidelines on non-sterile glove use to underpin evidence-based decision-making in nursing and other health professional education, improve patient outcomes, reduce healthcare costs and promote environmental sustainability in healthcare.
Implications: Inappropriate use of non-sterile gloves for preparing and administering intravenous antimicrobials hinders correct hand hygiene practices and increases healthcare-associated infections, healthcare costs and waste.
Impact: A critical gap in the existing evidence was a key finding of this review, highlighting the urgency for evidence-based guidelines to improve patient safety outcomes, reduce healthcare costs and promote environmental sustainability in healthcare.
Reporting Method: This scoping review adhered to the relevant EQUATOR guidelines and Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) reporting checklist.
Patient of Public Contribution: This study did not include patient or public involvement in its design, conduct or reporting.
Trial and Protocol Registration: The protocol was registered on Open Science Framework (https://doi.org/10.17605/OSF.IO/QY4J2).
Details
- Title
- Time to Hang Up the Gloves: A Scoping Review of Evidence on Non-Sterile Glove Use During Intravenous Antimicrobial Preparation and Administration
- Creators
- Natasya Raja Azlan - Edith Cowan UniversityDebbie Massey - Edith Cowan UniversityLesley Andrew - Edith Cowan UniversityAmanda Towell-Barnard - Edith Cowan UniversitySeng Giap Marcus Ang - Edith Cowan UniversityCarol Crevacore - Edith Cowan UniversityMartina Costello - Edith Cowan UniversityAaron Alejandro - Edith Cowan UniversityWeiting Liu - Edith Cowan UniversityNaila Zaman - Edith Cowan UniversityPeta-Anne Zimmerman - Griffith University (Australia, Gold Coast)
- Publication Details
- Journal of advanced nursing, Vol.First online
- Publisher
- Wiley; HOBOKEN
- Grant note
- Edith Cowan University, as part of the Wiley - Edith Cowan University agreement via the Council of Australian University Librarians
We would like to express our sincere gratitude to Lisa Munro, Edith Cowan University Librarian, for her invaluable assistance in developing a search strategy for the grey literature. Her expertise and support were instrumental in the success of this research. Open access publishing facilitated by Edith Cowan University, as part of the Wiley - Edith Cowan University agreement via the Council of Australian University Librarians.
- Identifiers
- 991013317625102368
- Copyright
- © 2025 The Author(s).
- Academic Unit
- Nursing; Faculty of Health
- Language
- English
- Resource Type
- Journal article