Journal article
The effect of exercise for improving bone health in cancer survivors - A systematic review and meta-analysis
Journal of science and medicine in sport, Vol.25(1), pp.31-40
01/2022
PMID: 34465518
Appears in Recent Faculty of Health Publications
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Source: InCites
Abstract
Objective
To evaluate the effectiveness of exercise for improving bone-related outcomes among cancer survivors.
Design
Systematic review and meta-analysis.
Methods
An electronic search using the following databases: SPORTDiscus, Science Direct, CINAHL, MEDLINE, Cochrane, Pubmed, Ebscohost, ProQuest Nursing and Allied Health Source.
Randomised, controlled, exercise trials involving cancer survivors were eligible. Effect data on bone mineral content (BMC) and density (BMD) outcomes were extracted. Risk of bias was assessed using the Physiotherapy Evidence Database tool. Standardised mean differences (SMD) were calculated to compare differences between exercise and usual care. Subgroup analyses were conducted to assess whether effect differed by exercise mode, intervention length, supervision, treatment, cancer type and risk of bias.
Results
Twenty-six trials were included, with intervention durations ranging between 12 weeks and 2 years. Most trials involved breast cancer (n = 13, 50%), and most interventions were supervised (n = 18, 69%) and evaluated mixed-mode (i.e., combined aerobic and resistance) exercise (n = 13, 50%). Significant effects in favour of exercise (aerobic, resistance, mixed-mode and other exercise) were observed for whole body BMD, hip BMD, trochanter BMD and femoral neck BMD (SMD range: 0.19–0.39, all p < 0.05) compared to usual care.
Conclusion
Participation in various modes (aerobic, resistance, mixed-mode and other) of supervised and unsupervised exercise is associated with improvements in BMD. The present results provide evidence for clinicians and other health care professionals (e.g., exercise physiologists and physiotherapists) to recommend exercise for cancer survivors to prevent bone loss during and following treatment.
Details
- Title
- The effect of exercise for improving bone health in cancer survivors - A systematic review and meta-analysis
- Creators
- Benjamin Singh - Greenslopes Private HospitalKellie Toohey - University of Canberra
- Publication Details
- Journal of science and medicine in sport, Vol.25(1), pp.31-40
- Publisher
- Elsevier
- Number of pages
- 10
- Identifiers
- 991013139813202368
- Copyright
- (c) 2021 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.
- Academic Unit
- Faculty of Health
- Language
- English
- Resource Type
- Journal article