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Published (Version of record)CC BY V4.0, Open Access
Published (Version of record)CC BY V4.0, Open
Journal article
The Emerging Role of Hypoxic Training for the Equine Athlete
Animals (Basel), Vol.13, 2799
03/09/2023
PMID: 37685063
Appears in Recent Faculty of Health Publications
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Source: InCites
Abstract
This paper provides a comprehensive discussion on the physiological impacts of hypoxic training, its benefits to endurance performance, and a rationale for utilizing it to improve performance in the equine athlete. All exercise-induced training adaptations are governed by genetics. Exercise prescriptions can be tailored to elicit the desired physiological adaptations. Although the application of hypoxic stimuli on its own is not ideal to promote favorable molecular responses, exercise training under hypoxic conditions provides an optimal environment for maximizing physiological adaptations to enhance endurance performance. The combination of exercise training and hypoxia increases the activity of the hypoxia-inducible factor (HIF) pathway compared to training under normoxic conditions. Hypoxia-inducible factor-1 alpha (HIF-1α) is known as a master regulator of the expression of genes since over 100 genes are responsive to HIF-1α. For instance, HIF-1-inducible genes include those critical to erythropoiesis, angiogenesis, glucose metabolism, mitochondrial biogenesis, and glucose transport, all of which are intergral in physiological adaptations for endurance performance. Further, hypoxic training could conceivably have a role in equine rehabilitation when high-impact training is contraindicated but a quality training stimulus is desired. This is achievable through purpose-built equine motorized treadmills inside commercial hypoxic chambers.
Details
- Title
- The Emerging Role of Hypoxic Training for the Equine Athlete
- Creators
- Allan Davie - Australian Equine Racing and Research Centre (Ballina, Australia)Rosalind Beavers - Southern Cross UniversityKristýna Hargitaiová - Cornell UniversityJoshua Denham - University of Southern Queensland
- Publication Details
- Animals (Basel), Vol.13, 2799
- Publisher
- MDPI
- Identifiers
- 991013141112502368
- Copyright
- © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
- Academic Unit
- Faculty of Health; Human Sciences
- Language
- English
- Resource Type
- Journal article