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Proteomic Insights into Edible Nut Seeds: Nutritional Value, Allergenicity, Stress Responses, and Processing Effects
Journal article   Open access   Peer reviewed

Proteomic Insights into Edible Nut Seeds: Nutritional Value, Allergenicity, Stress Responses, and Processing Effects

Qi Guo and Bronwyn J Barkla
Agronomy, Vol.15(10), pp.1-22
10/2025
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Published (Version of record)CC BY V4.0 Open Access
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Abstract

nut proteomics seed storage proteins allergens nut allergy lipid metabolism food processing; food safety stress response mass spectrometry sustainable crop improvement
Nuts, including tree nuts such as almonds, walnuts, cashews, and macadamias, as well as peanuts, are widely consumed for their health benefits owing to their high-quality protein content. Globally, the nut industry represents a multi-billion-dollar sector, with increasing demand driven by consumer interest in nutrition, functional foods, and plant based diets. Recent advances in proteomic technologies have enabled comprehensive analyses of nut seed proteins, shedding light on their roles in nutrition, allergenicity, stress responses, and food functionality. Seed storage proteins such as 2S albumins, 7S vicilins, and 11S legumins, are central to nutrition and allergenicity. Their behavior during processing has important implications for food safety. Proteomic studies have also identified proteins involved in lipid and carbohydrate metabolism, stress tolerance, and defense against pathogens. Despite technical challenges such as high lipid content and limited genomic resources for many nut species, progress in both extraction methods and mass spectrometry has expanded the scope of nut proteomics. This review underscores the central role of proteomics in improving nut quality, enhancing food safety, guiding allergen risk management, and supporting breeding strategies for sustainable crop improvement.

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