From the rhizomes of Begonia heracleifolia six known cucurbitacins (1-6) were isolated. Based on spectral data (1D and 2D 1H-, 13C-NMR, ESI- and CI- MS) the structures were established as cucurbitacin B (1), cucurbitacin D (2), 23,24-dihydrocucurbitacin D (3), 23,24-dihydrocucurbitacin F (4), 2-O-β- glucopyranosyl-cucurbitacin B (5), and 2-O-β-glucopyranosyl-cucurbitacin D (6). Four of them (3-6) were so far not reported as constituents of Begonia spp. Varyingly strong antiproliferative activity towards tumor and immune cells was observed for three compounds (1-3), due to different structural features.
Journal article
Phytochemical and biological investigation of Begonia heracleifolia
Planta Medica, Vol.64(4), pp.385-386
1998
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Abstract
Details
- Title
- Phytochemical and biological investigation of Begonia heracleifolia
- Creators
- B Frei - Swiss Federal Institute of Technology, ZurichM Heinrich - Albert-Ludwigs-UniversityD Herrmann - Dept. of Molecular PharmacologyJ E Orjala - Swiss Federal Institute of Technology, ZurichJ Schmitt - Dept. of Molecular PharmacologyO Sticher - Swiss Federal Institute of Technology
- Publication Details
- Planta Medica, Vol.64(4), pp.385-386
- Identifiers
- 1452; 991012820420102368
- Academic Unit
- Southern Cross Plant Science
- Resource Type
- Journal article