Journal article
Peripheral sensory neuropathy is associated with altered postocclusive reactive hyperemia in the diabetic foot
BMJ Open Diabetes Research & Care, Vol.4(1)
2016
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Source: InCites
Abstract
<p><p id="x-x-x-p-2"><strong>Objective</strong> This study examined whether the presence of peripheral sensory neuropathy or cardiac autonomic deficits is associated with postocclusive reactive hyperemia (reflective of microvascular function) in the diabetic foot. <p id="x-x-x-p-3"><strong>Research</strong> design and methods 99 participants with type 2 diabetes were recruited into this cross-sectional study. The presence of peripheral sensory neuropathy was determined with standard clinical tests and cardiac autonomic function was assessed with heart rate variation testing. Postocclusive reactive hyperemia was measured with laser Doppler in the hallux. Multiple hierarchical regression was performed to examine relationships between neuropathy and the peak perfusion following occlusion and the time to reach this peak.</p>
<p><strong>Results</strong>Peripheral sensory neuropathy predicted 22% of the variance in time to peak following occlusion (p <p id="x-x-x-p-5"><strong>Conclusions</strong> This study found an association between the presence of peripheral sensory neuropathy in people with diabetes and altered microvascular reactivity in the lower limb.</p>
Details
- Title
- Peripheral sensory neuropathy is associated with altered postocclusive reactive hyperemia in the diabetic foot
- Creators
- Alex Barwick - University of NewcastleJohn W Tessier - University of NewcastleXanne Janse de Jonge - University of NewcastleJames R Ivers - University of NewcastleVivienne H Chuter - University of New Castle
- Publication Details
- BMJ Open Diabetes Research & Care, Vol.4(1)
- Identifiers
- 3286; 991012820454502368
- Academic Unit
- Faculty of Health; School of Health and Human Sciences; Allied Health and Midwifery
- Resource Type
- Journal article