Outpatient transperineal prostate biopsy under local anaesthesia is safe, well tolerated and feasible

Anne Hong; Sarah Hemmingway; David Wetherell; Brendan Dias; Homayoun Zargar

doi:10.1111/ans.17593

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Outpatient transperineal prostate biopsy under local anaesthesia is safe, well tolerated and feasible

Journal article

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Outpatient transperineal prostate biopsy under local anaesthesia is safe, well tolerated and feasible

Anne Hong, Sarah Hemmingway, David Wetherell, Brendan Dias and Homayoun Zargar

ANZ journal of surgery, Vol.92(6), pp.1480-1485

06/2022

DOI: https://doi.org/10.1111/ans.17593

PMID: 35274426

Appears in Recent Faculty of Business, Law and Arts Publications

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Abstract

Life Sciences & Biomedicine

Science & Technology

Surgery

clinically significant prostate cancer

complications

detection rate

local anaesthesia

prostate biopsy

transperineal biopsy

Background Transperineal biopsy (TPB) of the prostate has been increasingly utilized as it has reduced infection risks. Traditionally however, it is performed under general anaesthesia, thus it carries a differing set of risks. Recently, new studies have performed TPB under local anaesthesia with success. In the present study, we explored our experience of performing TPB under local anaesthesia in an Australian cohort. Methods In this prospective study based at a metropolitan outpatient clinic, patients were provided with TPB under local anaesthesia. We assessed prostate cancer detection rates, complication rates and patient tolerability. Pain tolerability was assess using patient reported pain score on the visual analogue scale. Follow up data was collected at days 7 and 30 post-biopsy via telephone interview. Results A total of 48 patients were enrolled in this study between June 2020 and March 2021. Median age was 65.5 years and median PSA was 6.95 ng/mL. Clinically significant prostate cancer was detected in 58% of patients. During the procedure, pain scores were rated the highest during infiltration of local anaesthetic agent with a median score of 5. By the conclusion of the procedure, median pain score was 1. Vast majority of patients (85.4%) would opt for a repeat TPB under local anaesthesia should the need for prostate biopsy arise again. Two of our patients experienced infectious complications, and one experienced urinary retention. Conclusion Our data is in line with currently available data and confirms that TPB under local anaesthesia can be achieved in a safe and tolerable manner.

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Title: Outpatient transperineal prostate biopsy under local anaesthesia is safe, well tolerated and feasible
Creators: Anne Hong - Austin Hospital
Sarah Hemmingway - Southern Cross University
David Wetherell - Western Health
Brendan Dias - University of Melbourne
Homayoun Zargar - University of Melbourne
Publication Details: ANZ journal of surgery, Vol.92(6), pp.1480-1485
Publisher: Wiley
Number of pages: 6
Grant note: Mundipharma
Identifiers: 991013054708502368
Copyright: © 2022 The Authors. ANZ Journal of Surgery published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Surgeons. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Academic Unit: Faculty of Business, Law and Arts
Language: English
Resource Type: Journal article

Outpatient transperineal prostate biopsy under local anaesthesia is safe, well tolerated and feasible

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