Journal article
Nucleotide sequence of ub52 from the cnidarian Acropora millepora reveals high evolutionary conservation
Gene, Vol.178, pp.195-197
1996
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Source: InCites
Abstract
<p>We report the cDNA sequence encoding Ub52 from the cnidarian <em>Acropora millepora</em>. As in other eukaryotes, the N-terminal region of the deduced amino-acid sequence is a ubiquitin moiety and the C-terminal region CEP52, a protein component of the large ribosomal subunit. <em>A. millepora</em> Ub52 is highly homologous (>95% identical) with the corresponding <em>Drosophila</em> and vertebrate sequences, the cnidarian sequence having higher identity with these ‘higher’ metazoan homologs than does the corresponding <em>Caenorhabditis elegans</em> protein. However, the cnidarian sequence contains two unique substitutions in the ubiquitin moiety, Ser<sup>22</sup> and Thr<sup>28</sup>. Northern analysis indicates that <em>A. millepora</em> Ub52 is encoded by a small (< 800 nt) mRNA present in eggs and is first expressed after the early gastrula stage in embryonic development.</p>
Details
- Title
- Nucleotide sequence of ub52 from the cnidarian Acropora millepora reveals high evolutionary conservation
- Creators
- Heinrich Berghammer - James Cook UniversityDavid Hayward - Australian National UniversityPeter Lynton Harrison - Southern Cross UniversityDavid Miller - James Cook University
- Publication Details
- Gene, Vol.178, pp.195-197
- Identifiers
- 4173; 991012822053902368
- Academic Unit
- School of Environment, Science and Engineering; Science; Faculty of Science and Engineering
- Resource Type
- Journal article