Journal article
Lauric acid ameliorates lipopolysaccharide (LPS)-induced liver inflammation by mediating TLR4/MyD88 pathway in Sprague Dawley (SD) rats
Life Sciences, Vol.265, 118750
15/01/2021
PMID: 33188836
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Source: InCites
Abstract
Lipopolysaccharide (LPS) is an endotoxin that leads to inflammation in many organs, including liver. It binds to pattern recognition receptors, that generally recognise pathogen expressed molecules to transduce signals that result in a multifaceted network of intracellular responses ending up in inflammation. In this study, we used lauric acid (LA), a constituent abundantly found in coconut oil to determine its anti-inflammatory role in LPS-induced liver inflammation in Sprague Dawley (SD) rats.
Details
- Title
- Lauric acid ameliorates lipopolysaccharide (LPS)-induced liver inflammation by mediating TLR4/MyD88 pathway in Sprague Dawley (SD) rats
- Creators
- Hidayat Ullah Khan - Taylors UniversityKhurram Aamir - Taylors UniversityPatricia Regina Jusuf - University of MelbourneGautam Sethi - National University of SingaporeSreenivas Patro Sisinthy - University of Kuala LumpurReena Ghildyal - University of CanberraAditya Arya - University of Melbourne
- Publication Details
- Life Sciences, Vol.265, 118750
- Publisher
- Elsevier Inc
- Identifiers
- 991013035750602368
- Academic Unit
- National Centre for Naturopathic Medicine
- Language
- English
- Resource Type
- Journal article