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Published (Version of record)CC BY-NC V4.0, Open Access
Published (Version of record)CC BY-NC V4.0, Open
Journal article
Hypoxia as a physiological cue and pathological stress for coral larvae
Molecular Ecology, Vol.31(2), pp.571-587
01/2022
PMID: 34716959
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Source: InCites
Abstract
Ocean deoxygenation events are intensifying worldwide and can rapidly drive adult corals into a state of metabolic crisis and bleaching-induced mortality, but whether coral larvae are subject to similar stress remains untested. We experimentally exposed apo-symbiotic coral larvae of Acropora selago to deoxygenation stress with subsequent reoxygenation aligned to their night-day light cycle, and followed their gene expression using RNA-Seq. After 12 h of deoxygenation stress (~2 mg O2/L), coral planulae demonstrated a low expression of HIF-targeted hypoxia response genes concomitant with a significantly high expression of PHD2 (a promoter of HIFα proteasomal degradation), similar to corresponding adult corals. Despite exhibiting a consistent swimming phenotype compared to control samples, the differential gene expression observed in planulae exposed to deoxygenation-reoxygenation suggests a disruption of pathways involved in developmental regulation, mitochondrial activity, lipid metabolism, and O2-sensitive epigenetic regulators. Importantly, we found that treated larvae exhibited a disruption in the expression of conserved HIF-targeted developmental regulators, for example, Homeobox (HOX) genes, corroborating how changes in external oxygen levels can affect animal development. We discuss how the observed deoxygenation responses may be indicative of a possible acclimation response or alternatively may imply negative latent impacts for coral larval fitness.
Details
- Title
- Hypoxia as a physiological cue and pathological stress for coral larvae
- Creators
- Rachel Alderdice - University of Technology, SydneyMathieu Pernice - University of Technology, SydneyAnny Cárdenas - University of KonstanzDavid J Hughes - University of Technology, SydneyPeter L Harrison - Southern Cross UniversityNadine Boulotte - Southern Cross UniversityKatie Chartrand - James Cook UniversityMichael Kühl - University of Technology, SydneyDavid J Suggett - University of Technology SydneyChristian R Voolstra - University of Konstanz
- Publication Details
- Molecular Ecology, Vol.31(2), pp.571-587
- Publisher
- Wiley-Blackwell Publishing Ltd.
- Grant note
- Australian Research Council. Grant Number: DP180100074 Deutsche Forschungsgemeinschaft. Grant Numbers: 433042944, 458901010 Gordon and Betty Moore Foundation. Grant Number: GBMF9206 Small Business Innovation Research. Grant Number: TF6.7.1
- Identifiers
- 991012978266602368
- Copyright
- © 2021 The Authors. Molecular Ecology published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
- Academic Unit
- Faculty of Science and Engineering; Marine Ecology Research Centre; School of Environment, Science and Engineering; Science
- Language
- English
- Resource Type
- Journal article