Journal article
High expression of MHC I in the tibialis anterior muscle of a paraplegic patient
Muscle & Nerve, Vol.22(12), pp.1731-1737
1999
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Source: InCites
Abstract
<p>A long-term paraplegic man presented exclusively (>99%) myosin heavy chain I (MHC I) in the tibialis anterior muscle (TA). This was coupled to a slow speed of contraction, a high resistance to fatigue, and a rapid resynthesis of phosphocreatine after an electrically evoked fatiguing contraction when compared with the TA muscles of 9 other paraplegic individuals. In contrast, the MHC composition of his vastus lateralis, gastrocnemius, and soleus muscles was that expected of a muscle from a spinal cord injured individual. This information may be of clinical importance in terms of the expected morphological and functional adaptations of skeletal muscle to different types of electrical stimulation therapy</p>
Details
- Title
- High expression of MHC I in the tibialis anterior muscle of a paraplegic patient
- Creators
- Andreas Hartkopp - Copenhagen Muscle Research CentreJesper L Andersen - Copenhagen Muscle Research CentreStephen DR Harridge - Copenhagen Muscle Research CentreClarissa Crone - Copenhagen University HospitalsTom Gruschy-Knudsen - University of CopenhagenMichael Kjaer - Copenhagen Muscle Research CentreMizuno Masao - University of CopenhagenAivaras Ratkevicius - University of CopenhagenBjorn Quistorff - University of CopenhagenShi Zhou - Southern Cross UniversityFin Biering-Sorensen - Copenhagen Muscle Research Centre
- Publication Details
- Muscle & Nerve, Vol.22(12), pp.1731-1737
- Identifiers
- 1430; 991012820970102368
- Academic Unit
- Faculty of Health; School of Health and Human Sciences; Human Sciences
- Resource Type
- Journal article