Journal article
Green coffee ameliorates components of diet-induced metabolic syndrome in rats
Journal of Functional Foods, Vol.57(June 2019), pp.141-149
10/04/2019
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Source: InCites
Abstract
Metabolic syndrome, especially obesity, increases the risk of type 2 diabetes and cardiovascular disease. We hypothesised that green coffee will attenuate metabolic, cardiovascular and liver parameters in high-carbohydrate high-fat diet-fed rats. Male Wistar rats (8–9 weeks old) were divided into 6 groups and fed for 16 weeks with either corn starch diet (C), C with either 5% green or decaffeinated green coffee in food for the last 8 weeks, high-carbohydrate high-fat diet (H) or H with either 5% green or decaffeinated green coffee in food for the last 8 weeks. Green coffee contained chlorogenic acids, trigonelline, caffeine and diterpenoids; decaffeinated green coffee contained these compounds but no caffeine. Green coffee attenuated body weight, systolic blood pressure, inflammation in the heart and liver and diastolic stiffness without improving glucose sensitivity or plasma lipids. We suggest that chlorogenic acids, trigonelline and diterpenoids in green coffee attenuate diet-induced abnormalities in heart and liver.
Details
- Title
- Green coffee ameliorates components of diet-induced metabolic syndrome in rats
- Creators
- Nikhil S Bhandarkar - School of Health and Wellbeing, University of Southern Queensland, Toowoomba, QLD 4350, AustraliaPeter Mouatt - Southern Cross Plant Science, Southern Cross University, Lismore, NSW 2480, AustraliaLindsay Brown - School of Health and Wellbeing, University of Southern Queensland, Toowoomba, QLD 4350, AustraliaSunil K Panchal - Functional Foods Research Group, University of Southern Queensland, Toowoomba, QLD 4350, Australia
- Publication Details
- Journal of Functional Foods, Vol.57(June 2019), pp.141-149
- Publisher
- Elsevier BV
- Identifiers
- 991012927079902368
- Copyright
- © 2019 Elsevier Ltd. All rights reserved.
- Academic Unit
- Southern Cross Plant Science
- Language
- English
- Resource Type
- Journal article