Journal article
Ginger for Pain Management in Primary Dysmenorrhea: A Systematic Review and Meta-Analysis
Journal of integrative and complementary medicine, Vol.30(11), pp.1016-1030
01/11/2024
PMID: 38770631
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Source: InCites
Abstract
Background: Primary dysmenorrhea is a common gynecological disorder that affects many women of reproductive age. Ginger, a widely used spice with anti-inflammatory properties, has been suggested as a potential treatment for the painful cramps associated with this condition.
Objective: The aim of this systematic review and meta-analysis was to evaluate the efficacy of ginger for pain management in primary dysmenorrhea.
Methods: Our systematic review was registered in Prospero (CRD42023418001). Six English (PubMed, Scopus, Web of Science, PsycINFO, CINAHL complete, and Cochrane) and one Persian electric database (SID) was searched up to May 2023 for English or Persian studies that measure the effect of ginger on pain in dysmenorrhea. The Cochrane tool was used to assess the risk of bias of the included studies. Random effects meta-analyses were performed to obtain standardized mean differences (SMD) and 95% confidence intervals (CI).
Results: Out of the 804 articles initially identified from the search, 24 were included for qualitative analysis and 12 for quantitative analysis after a full-text evaluation. The combined results of the studies indicate that ginger is notably more effective than placebo in reducing both the intensity (SMD = −1.13; 95% CI = −1.59 to −0.68, I2 = 81.05%) and duration of pain (SMD = −0.29; 95% CI = −0.46 to −0.12). There were no differences between ginger and nonsteroidal anti-inflammatory drugs (NSAIDs) (SMD = 0.01; 95% CI = −0.24 to 0.25), or exercise (SMD = 0.06; 95% CI = −0.66 to 0.78) for pain intensity. Safety-related data were infrequently reported.
Conclusions: The results of this meta-analysis suggest that ginger can effectively reduce pain associated with dysmenorrhea. The findings are limited due to risk of bias in the included studies and the unclear risk-benefit ratio.
Details
- Title
- Ginger for Pain Management in Primary Dysmenorrhea: A Systematic Review and Meta-Analysis
- Creators
- Reza Moshfeghinia - Shiraz University of Medical SciencesNastaran Salmanpour - Shiraz University of Medical SciencesHamed Ghoshouni - Shiraz University of Medical SciencesHossein Gharedaghi - Zanjan University of Medical SciencesRoghayeh Zare - Shahid Sadoughi University of Medical Sciences and Health ServicesHolger Cramer - University Hospital Tübingen (Tübingen, Germany)Ghazaleh Heydarirad - Shahid Beheshti University of Medical SciencesMehdi Pasalar - Shiraz University of Medical Sciences
- Publication Details
- Journal of integrative and complementary medicine, Vol.30(11), pp.1016-1030
- Publisher
- Mary Ann Liebert, Inc. Publishers
- Identifiers
- 991013190413302368
- Copyright
- Copyright 2024, Mary Ann Liebert, Inc., publishers.
- Academic Unit
- National Centre for Naturopathic Medicine
- Language
- English
- Resource Type
- Journal article