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Extracellular amoebal-vesicles: potential transmission vehicles for respiratory viruses
Journal article   Open access

Extracellular amoebal-vesicles: potential transmission vehicles for respiratory viruses

Rafik Dey, Melanie A Folkins and Nicholas J Ashbolt
NPJ Biofilms and Microbiomes, Vol.7, 25 (2021)
2021
PMID: 33731696
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Extracellular amoebal-vesicles: potential transmission vehicles for respiratory virusesView
Published (Version of record) Open

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Abstract

Human respiratory syncytial virus (RSV) is a major cause of acute respiratory tract infections in children and immunocompromised adults worldwide. Here we report that amoebae-release respirable-sized vesicles containing high concentrations of infectious RSV that persisted for the duration of the experiment. Given the ubiquity of amoebae in moist environments, our results suggest that extracellular amoebal-vesicles could contribute to the environmental persistence of respiratory viruses, including potential resistance to disinfection processes and thereby offering novel pathways for viral dissemination and transmission.

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