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Examining efficacy and safety of ethyl acetate extract from Allium hirtifolium as complementary therapy in COVID-19: A randomized, multicenter, controlled clinical trial
Journal article   Open access   Peer reviewed

Examining efficacy and safety of ethyl acetate extract from Allium hirtifolium as complementary therapy in COVID-19: A randomized, multicenter, controlled clinical trial

Mansour Amin, Mandana Pouladzadeh, Mohammad Jaafar Yadyad, Roshanak Roshanfard, Mohamad Hasan Pipelzadeh, Afshin Talebi, Behzad Sharif Maakhmalzadeh, Mehdi Bijanzadeh, Nasrin Rakipour, Gholamreza Alizadehattar, …
Avicenna journal of phytomedicine, Vol.14(6), pp.699-710
11/2024
PMID: 40259955
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Examining efficacy and safety of ethyl acetate extract from Allium hirtifolium as complementary therapy in COVID-19View
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Abstract

ARS-CoV-2 COVID-19 Lopinavir Ritonavir Shallomin syrup Drug safety
Objective: Given the apparent life-threatening nature of COVID19, finding an effective treatment is under investigation. Materials and Methods: We assessed effect of shallomin oral syrup (co IranAmin (R)) as a complementary treatment to improve the clinical outcomes in COVID-19 patients. Patients in the control group received the approved treatment protocol (lopinavir/ritonavir), while those in the intervention group were treated with the oral syrup shallomin in addition to the approved treatment. Clinical status of treated patients was recorded and compared. Results: There were meaningful differences between the two groups regarding shortened length of hospital stay and the recovery time for cough, myalgia, sore throat, and shortness of breath. No side effect occurred in the intervention group compared to the control group in terms of biochemical and hematological factors. Conclusion: It seems that the treatment with shallomin syrup showed remarkable contribution to the recovery of COVID-19 induced symptoms in the patients under lopinavir/ritonavir therapy.

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