Journal article
Diabetes mellitus and functional limitations among older adults: Evidence from a large, representative Ghanaian aging study
Journal of psychosomatic research, Vol.174, 111481
11/2023
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Abstract
Objectives
Literature linking diabetes mellitus (DM) to functional status is limited in low- and middle-income countries. Importantly, factors influencing this association are even less understood. This study aims to examine the association of DM with functional limitations (FL) in older adults and to identify potential factors influencing this association.
Methods
In a cross-sectional analysis, we examined the association between DM and basic and instrumental activities of daily living-related FL in 1201 adults aged ≥50 years from the Aging, Health, Psychological Well-being, and Health-seeking Behavior Study. DM was defined as a self-report of physician diagnosis. The associations were assessed using hierarchical regression estimates and bootstrapping technique via the Hayes PROCESS macro program.
Results
The prevalence of DM and FL was 10.1% and 36.1%, respectively, with OR = 2.50 (95%CI = 1.59–3.92) after accounting for sociodemographic factors, smoking, alcohol use, self-rated health, loneliness, and sleep quality. After full adjustment, polytomous regressions showed that the association of DM with FL increased with the number of FL (i.e., OR = 1.60 for 1–2, OR = 1.88 for 3–5, and OR = 2.0o for >5 FL compared with no FL). However, this association was attenuated after controlling for physical activity (OR = 2.06, 95%CI = 1.28–3.31), hypertension (OR = 1.87, 95%CI = 1.14–2.99), stroke (OR = 1.82, 95%CI = 1.20–2.93), and pain facets (OR = 1.80, 95%CI = 1.04–3.02). PA thus mediated 40.39% of the DM-FL association.
Conclusions
In this representative study, older adults with DM showed higher odds for FL, and this association was partially explained by physical activity and health variables. Investing in a holistic management approach might be helpful for public health planning efforts to address DM-induced FL in old age.
Details
- Title
- Diabetes mellitus and functional limitations among older adults: Evidence from a large, representative Ghanaian aging study
- Creators
- Razak M. Gyasi - Southern Cross UniversityJulius Odei - Kwame Nkrumah University of Science and TechnologyMohammed Gazali Hambali - Kwame Nkrumah University of Science and TechnologyNelson Gyasi-Boadu - Kwame Nkrumah University of Science and TechnologyBernard Obeng - Kwame Nkrumah University of Science and TechnologyMoses Asori - University of North Carolina at CharlotteAndré Hajek - University Medical Center Hamburg-EppendorfLouis Jacob - University of Versailles Saint-Quentin-en-YvelinesYvonne Ami Dodzi Adjakloe - University of Cape CoastJones Opoku-Ware - Kwame Nkrumah University of Science and TechnologyLee Smith - Anglia Ruskin UniversityAi Koyanagi - Catalan Institution for Research and Advanced Studies
- Publication Details
- Journal of psychosomatic research, Vol.174, 111481
- Publisher
- Elsevier Inc
- Identifiers
- 991013139913002368
- Copyright
- © 2023 Elsevier Inc. All rights reserved.
- Academic Unit
- National Centre for Naturopathic Medicine
- Language
- English
- Resource Type
- Journal article