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Published (Version of record)CC BY V4.0, Open Access
Published (Version of record)CC BY V4.0, Open
Journal article
Comparison of Citrated Whole Blood to Native Whole Blood for Coagulation Testing Using the Viscoelastic Coagulation Monitor (VCM Vet™) in Horses
Animals, Vol.14(19), pp.1-12
08/10/2024
PMID: 39409841
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Abstract
Viscoelastic monitoring of horse coagulation is increasing due to its advantages over traditional coagulation testing. The use of a point-of-care viscoelastic coagulation monitor (VCM Vet™) has been validated for use in horses using native whole blood (NWB) but has not been assessed using citrated whole blood (CWB), a technique that might have advantages in practicality and precision. Blood was collected from 70 horses, tested in duplicate immediately using NWB (T0), and stored at room temperature as CWB for testing in duplicate at 1 (T1) and 4 (T4) hours after venipuncture for comparison to NWB. Of these horses, 20 were classified as clinically healthy and used to determine reference intervals for CWB at 1 and 4 h post-collection. There were clinically relevant differences in all measured viscoelastic parameters of CWB compared to NWB meaning that they cannot be used interchangeably. These differences were not consistent at T1 and T4 meaning the resting time of CWB influences the results and should be kept consistent. The use of CWB in this study also resulted in more machine errors when compared to NWB resulting in measurements that might not be interpretable.
Details
- Title
- Comparison of Citrated Whole Blood to Native Whole Blood for Coagulation Testing Using the Viscoelastic Coagulation Monitor (VCM Vet™) in Horses
- Creators
- Jessica R Vokes - Massey UniversityAmy L Lovett - Massey UniversityMax C de Kantzow - Department of Agriculture, Fisheries and ForestryChris W Rogers - Massey UniversityPamela A Wilkins - University of Illinois Urbana-ChampaignBenjamin W Sykes - Massey University
- Publication Details
- Animals, Vol.14(19), pp.1-12
- Publisher
- MDPI AG
- Grant note
- Research funding was provided by the Massey University Lewis Fitch Veterinary Research Fund.
- Identifiers
- 991013225624202368
- Copyright
- © 2024 by the authors.
- Academic Unit
- Faculty of Science and Engineering
- Language
- English
- Resource Type
- Journal article