Journal article
Cognition in breast cancer survivors: A pilot study of interval and continuous exercise
Journal of science and medicine in sport, Vol.22(5), pp.580-585
05/2019
PMID: 30554923
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Source: InCites
Abstract
Objectives
The current study investigated the effects of two exercise interventions on cognitive function amongst breast cancer survivors.
Design
Pilot randomised-controlled trial.
Methods
Seventeen female cancer survivors (mean: 62.9 ± 7.8 years) were randomised into three groups: high-intensity interval training (HIIT, n = 6); moderate-intensity continuous training (MOD, n = 5); or wait-list control (CON, n = 6). The HIIT and MOD groups exercised on a cycle ergometer 3 days/week for 12-weeks. Primary outcomes were cognitive function assessments utilising CogState. Secondary outcomes were resting middle cerebral artery blood flow velocity, cerebrovascular reactivity and aerobic fitness (VO2peak). Data were analysed with General Linear Mixed Models and Cohen’s d effect sizes were calculated.
Results
All 17 participants who were randomised were available for follow-up analysis and adherence was similar for HIIT and MOD (78.7 ± 13.2% vs 79.4 ± 12.0%; p = 0.93). Although there were no significant differences in the cognitive and cerebrovascular outcomes, HIIT produced moderate to large positive effects in comparison to MOD and CON for outcomes including episodic memory, working memory, executive function, cerebral blood flow and cerebrovascular reactivity. HIIT significantly increased VO2peak by 19.3% (d = 1.28) and MOD had a non-significant 5.6% (d = 0.72) increase, compared to CON which had a 2.6% decrease.
Conclusions
This study provides preliminary evidence that HIIT may be an effective exercise intervention to improve cognitive performance, cerebrovascular function and aerobic fitness in breast cancer survivors. Considering the sample size is small, these results should be confirmed through larger clinical trials.
Details
- Title
- Cognition in breast cancer survivors: A pilot study of interval and continuous exercise
- Creators
- Joseph M. Northey - University of CanberraKate L. Pumpa - University of CanberraClare Quinlan - University of CanberraAshley Ikin - University of CanberraKellie Toohey - University of CanberraDisa J. Smee - University of CanberraBen Rattray - University of Canberra
- Publication Details
- Journal of science and medicine in sport, Vol.22(5), pp.580-585
- Publisher
- Elsevier Ltd
- Identifiers
- 991013139713702368
- Copyright
- © 2018 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.
- Academic Unit
- Faculty of Health
- Language
- English
- Resource Type
- Journal article