Journal article
Cognition, ADHD Symptoms, and Functional Impairment in Children and Adolescents With Neurofibromatosis Type 1
Journal of attention disorders, Vol.25(8), pp.1177-1186
06/2021
PMID: 31838937
Metrics
49 Record Views
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites
Abstract
Objective: We examined the contribution of attention and executive cognitive processes to ADHD symptomatology in NF1, as well as the relationships between cognition and ADHD symptoms with functional outcomes. Methods: The study sample consisted of 141 children and adolescents with NF1. Children were administered neuropsychological tests that assessed attention and executive function, from which latent cognitive variables were derived. ADHD symptomatology, adaptive skills, and quality of life (QoL) were assessed using parent-rated questionnaires. Path analyses were conducted to test relationships among cognitive functioning, ADHD symptomatology, and functional outcomes. Results: Significant deficits were observed on all outcome variables. Cognitive variables did not predict ADHD symptomatology. Neither did they predict functional outcomes. However, elevated ADHD symptomatology significantly predicted functional outcomes. Conclusion: Irrespective of cognitive deficits, elevated ADHD symptoms in children with NF1 negatively impact daily functioning and emphasize the importance of interventions aimed at minimizing ADHD symptoms in NF1.
Details
- Title
- Cognition, ADHD Symptoms, and Functional Impairment in Children and Adolescents With Neurofibromatosis Type 1
- Creators
- Jonathan M. Payne - Murdoch Childrens Research InstituteKristina M. Haebich - Royal Children's HospitalRachel MacKenzie - La Trobe UniversityKarin S. Walsh - Children’s National Health SystemStephen J. C. Hearps - Murdoch Childrens Research InstituteDavid Coghill - Royal Children's HospitalBelinda Barton - Children's Hospital at WestmeadNatalie A. Pride - Children's Hospital at WestmeadNicole J. Ullrich - Boston Children's HospitalJames H. Tonsgard - Comer Children's HospitalDavid Viskochil - University of UtahElizabeth K. Schorry - Cincinnati Children's Hospital Medical CenterLaura Klesse - The University of Texas Southwestern Medical CenterMichael J. Fisher - Children's Hospital of PhiladelphiaDavid H. Gutmann - Washington University in St. LouisTena Rosser - Children's Hospital of Los AngelesRoger J. Packer - Children’s National Health SystemBruce Korf - University of Alabama at BirminghamMaria T. Acosta - Children’s National Health SystemMark A. Bellgrove - Monash UniversityKathryn N. North - Royal Children's Hospital
- Publication Details
- Journal of attention disorders, Vol.25(8), pp.1177-1186
- Publisher
- Sage
- Number of pages
- 10
- Grant note
- Murdoch Children's Research Institute Clinician-Scientist Fellowship National Health and Medical Research Council (NHMRC) of Australia W81XWH-05-1-0615 / United States Army Medical Research and Materiel Command, Office of the Congressionally Directed Medical Research Programs, Department of Defense Neurofibromatosis Research Program
- Identifiers
- 991013093609102368
- Copyright
- © The Author(s) 2019.
- Academic Unit
- Faculty of Health
- Language
- English
- Resource Type
- Journal article