Journal article
COVID-19-associated encephalitis
Global biosecurity, Vol.5(1), pp.1-18
17/02/2023
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Abstract
COVID-19 associated encephalitis has been reported in patients infected with SARS-CoV-2 since February 2020. The index case was reported in Japan, but since then, reports have emerged worldwide, with a global incidence rate of 0.215%, and regional incidence rates of up to 18%. While in the acute phase of infection, COVID-19-associated encephalitis can biologically mimic infectious limbic encephalitis, immune-inflammatory-mediated encephalopathy, herpes simplex encephalitis, produce hyperintensities in multiple regions of the brain, and mimic Alzheimer’s Disease. With a high mortality rate of 13.4%, COVID-19-associated encephalitis poses a significant burden on health systems and resources, requiring a combination diagnostic approach, supportive treatment regimens, and regular monitoring for secondary worsening of symptoms. COVID-19-associated encephalitis can emerge up to six weeks post-infection, and elevated risk levels can persist for six months post-infection. Despite emerging evidence and research, significant longitudinal research is required to ascertain the true prevalence and lifetime health risk of developing encephalitis following SARS-CoV-2 infection. This report aims to provide a summary of COVID-19 associated encephalitis.
Details
- Title
- COVID-19-associated encephalitis
- Creators
- Braidy Sutton - University of New South Wales (Australia, Sydney)Damian Honeyman - University of New South Wales (Australia, Sydney)Adriana Notaras - The Kirby Institute (UNSW, Sydney)Ashley Quigley - The Kirby Institute (UNSW, Sydney)
- Publication Details
- Global biosecurity, Vol.5(1), pp.1-18
- Publisher
- University of New South Wales
- Identifiers
- 991013376549802368
- Copyright
- © 2023 The Author(s).
- Academic Unit
- Faculty of Health
- Language
- English
- Resource Type
- Journal article