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Associations Between Fatigue and Disability, Depression, Health-Related Hardiness and Quality of Life in People with Stroke
Journal article   Peer reviewed

Associations Between Fatigue and Disability, Depression, Health-Related Hardiness and Quality of Life in People with Stroke

David Sibbritt, Jessica Bayes, Wenbo Peng, Jane Maguire and Jon Adams
Journal of stroke and cerebrovascular diseases, Vol.31(7), 106543
07/2022
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2022.106543
PMID: 35525062

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Abstract

Fatigue Health-related hardiness Quality of life Rehabilitation Stroke
Background Stroke is a common cause of mortality and morbidity which affects approximately 17 million people globally each year. Common symptoms associated with stroke are physical disabilities, impaired cognitive functions, depression, and fatigue, all of which can significantly impact health-related quality of life (HRQoL). To date, no research has explored the inter-relationship among fatigue, disability, depression, health-related hardiness, and quality of life in stroke survivors. Methods Data was obtained from a sub-study of the 45 and Up Study; including 576 Australian adults who had been diagnosed with a stroke. The cross-sectional questionnaire obtained demographic and health status information, as well as clinical measures and stroke-related measures. Associations among fatigue and disability, depression, health-related hardiness and quality of life were analysed using a linear regression model. Results In comparison to those participants with no stroke-related disability, those with slight (β = 1.141; p = 0.008), moderate (β = 3.250; p < 0.001) or severe (β = 3.526; p < 0.001) disability had significantly higher fatigue scores. For every one unit increase in the depression score, the fatigue score increased by 1.502 points (p < 0.001). For every one unit increase in the health-related hardiness score, the fatigue score decreased by 0.054 points (p = 0.044). For every one unit increase in the quality of life score, the fatigue score decreased by 0.068 points (p < 0.001). Conclusion This study found significant associations among fatigue and disability, depression, health-related hardiness, and quality of life in stroke survivors. Accurate detection and management of fatigue may help improve the rehabilitation of stroke survivors.

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