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Assessment of patient-to-patient and intra-individual human abdominal skin immune cell variability117.14 kB
Published (Version of record)CC BY-NC-SA V4.0, Open Access
Published (Version of record)CC BY-NC-SA V4.0, Open
Journal article
Assessment of patient-to-patient and intra-individual human abdominal skin immune cell variability
Archives of medical science, Vol.18(6), pp.1683-1688
07/11/2022
Appears in Recent Faculty of Health Publications
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Source: InCites
Abstract
Introduction:
The objective of the study was to characterize the baseline intra-individual and inter-individual variability of immune cell subsets within abdominoplasty skin specimens.
Material and methods:
Abdominoplasty biopsies were taken from 5 patients and analysed using the Vectra 3 automated quantitative pathology imaging system with inForm software.
Results:
Adjacent skin regions demonstrated intra-patient variability in immune subset counts ranging from 1- to 5-fold. Inter-variability between patients was approximately 2- to 7-fold for most subsets, except for HLA-DR+ antigen presenting cells, which varied 19-fold.
Conclusions:
Our data highlight the importance of including multiple patients and multiple patient samples when designing dermatological studies that utilise abdominoplasty skin.
Details
- Title
- Assessment of patient-to-patient and intra-individual human abdominal skin immune cell variability
- Creators
- Margaret Veitch - University of QueenslandCraig Layt - The Layt Clinic, Southport, AustraliaEmma Raymond - Royal Brisbane and Women's HospitalAndrew J. Croaker - Wesley HospitalJames W. Wells - University of QueenslandAndy Croaker - Southern Cross University
- Publication Details
- Archives of medical science, Vol.18(6), pp.1683-1688
- Publisher
- Termedia Publishing House
- Identifiers
- 991013075124402368
- Copyright
- © 2022 Termedia & Banach. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY -NC -SA 4.0). License (http://creativecommons.org/licenses/by-nc-sa/4.0/).
- Academic Unit
- Faculty of Health
- Language
- English
- Resource Type
- Journal article