Journal article
Assessing the risk of epidemic dropsy from black salve use
Journal of Applied Toxicology, Vol.38(10), pp.1274-1281
10/2018
PMID: 29603306
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Source: InCites
Abstract
Epidemic dropsy is a potentially life-threatening condition resulting from the ingestion of argemone oil derived from the seeds of Argemone mexicana Linn. Exposure to argemone oil is usually inadvertent, arising from mustard cooking oil adulteration. Sanguinarine, an alkaloid present in argemone oil, has been postulated as a causative agent with the severity of epidemic dropsy correlating with plasma sanguinarine levels. Cases of epidemic dropsy have also been reported following the topical application of argemone containing massage oil. Black salve, a topical skin cancer therapy also contains sanguinarine, but at significantly higher concentrations than that reported for contaminated massage oil. Although not reported to date, a theoretical risk therefore exists of black salve inducing epidemic dropsy. This literature review explores the presentation and pathophysiology of epidemic dropsy and assesses the risk of it being induced by black salve.
Details
- Title
- Assessing the risk of epidemic dropsy from black salve use
- Creators
- Andrew Croaker - Southern Cross UniversityGraham J King - Southern Cross UniversityJohn H Pyne - University of QueenslandShailendra Anoopkumar‐Dukie - Griffith UniversityLei Liu - Southern Cross University
- Publication Details
- Journal of Applied Toxicology, Vol.38(10), pp.1274-1281
- Publisher
- John Wiley & Sons Ltd.
- Number of pages
- 8
- Identifiers
- 991012925443602368
- Copyright
- Copyright © 2018 John Wiley & Sons, Ltd.
- Academic Unit
- Faculty of Health; Science; Southern Cross Plant Science; Faculty of Science and Engineering
- Language
- English
- Resource Type
- Journal article