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Published (Version of record)CC BY-NC-ND V4.0, Open Access
Published (Version of record)CC BY-NC-ND V4.0, Open
Journal article
Arnold's nerve cough reflex: evidence for chronic cough as a sensory vagal neuropathy
Journal of thoracic disease, Vol.6(S7), pp.S748-S752
25/10/2014
PMID: 25383210
Metrics
Abstract
Arnold's nerve ear-cough reflex is recognised to occur uncommonly in patients with chronic cough. In these patients, mechanical stimulation of the external auditory meatus can activate the auricular branch of the vagus nerve (Arnold's nerve) and evoke reflex cough. This is an example of hypersensitivity of vagal afferent nerves, and there is now an increasing recognition that many cases of refractory or idiopathic cough may be due to a sensory neuropathy of the vagus nerve. We present two cases where the cause of refractory chronic cough was due to sensory neuropathy associated with ear-cough reflex hypersensitivity. In both cases, the cough as well as the Arnold's nerve reflex hypersensitivity were successfully treated with gabapentin, a treatment that has previously been shown to be effective in the treatment of cough due to sensory laryngeal neuropathy (SLN).
Details
- Title
- Arnold's nerve cough reflex: evidence for chronic cough as a sensory vagal neuropathy
- Creators
- Nicole M Ryan - University of Newcastle AustraliaPeter G. Gibson - University of Newcastle AustraliaSurinder S. Birring - King’s College London (London, UK)
- Publication Details
- Journal of thoracic disease, Vol.6(S7), pp.S748-S752
- Publisher
- AME PUBLISHING COMPANY
- Identifiers
- 991013184712202368
- Copyright
- © Pioneer Bioscience Publishing Company. All rights reserved.
- Academic Unit
- Faculty of Health
- Language
- English
- Resource Type
- Journal article