Journal article
Anti-inflammatory and immunomodulatory properties of Carica papaya
Journal of immunotoxicology, Vol.13(4), pp.590-602
2016
PMID: 27416522
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Source: InCites
Abstract
Chronic inflammation is linked with the generation and progression of various diseases such as cancer, diabetes and atherosclerosis, and anti-inflammatory drugs therefore have the potential to assist in the treatment of these conditions. Carica papaya is a tropical plant that is traditionally used in the treatment of various ailments including inflammatory conditions. A literature search was conducted by using the keywords "papaya", "anti-inflammatory and inflammation" and "immunomodulation and immune" along with cross-referencing. Both in vitro and in vivo investigation studies were included. This is a review of all studies published since 2000 on the anti-inflammatory activity of papaya extracts and their effects on various immune-inflammatory mediators. Studies on the anti-inflammatory activities of recognized phytochemicals present in papaya are also included. Although in vitro and in vivo studies have shown that papaya extracts and papaya-associated phytochemicals possess anti-inflammatory and immunomodulatory properties, clinical studies are lacking.
Details
- Title
- Anti-inflammatory and immunomodulatory properties of Carica papaya
- Creators
- Saurabh Pandey - University of QueenslandPeter J Cabot - University of QueenslandP. Nicholas Shaw - University of QueenslandAmitha K Hewavitharana (Corresponding Author) - University of Queensland
- Publication Details
- Journal of immunotoxicology, Vol.13(4), pp.590-602
- Publisher
- Taylor & Francis
- Identifiers
- 991012894199702368
- Academic Unit
- Faculty of Science and Engineering; Southern Cross Plant Science; Science
- Language
- English
- Resource Type
- Journal article