Alkaloids and limonoids from Bouchardatia neurococca: systematic significance

Five alkaloids, four β-indoloquinazoline and one furoquinoline, and four terpenoids, three limonoids and one modified sesquiterpene, have been obtained from the aerial parts of Bouchardatia neurococca (Rutaceae). Two of the alkaloids, 1,2-dihydroxyrutaecarpine and 2-(2-[3-formylindolyl])-(3H)-quinazolin-4-one (bouchardatine), and two of the limonoids, 23-oxo-21ξ-hydroxy-21,23-dihydroveprisone (veprisonic acid) and 21-oxo-23ξ-hydroxy-21,23-dihydroveprisone (isoveprisonic acid) are new. The pattern of secondary metabolites isolated is rather unusual in the Rutaceae and is reminiscent of Tetradium, a genus with which Bouchardatia has not previously been associated. Five alkaloids, four β-indoloquinazoline and one furoquinoline, and four terpenoids, three limonoids and one modified sesquiterpene, have been obtained from the aerial parts of Bouchardatia neurococca (Rutaceae). The pattern of secondary metabolites isolated is rather unusual in the Rutaceae and is reminiscent of Tetradium, a genus with which Bouchardatia has not previously been associated.