Journal article
Accelerated long-term forgetting in children with genetic generalized epilepsy: The temporal trajectory and contribution of executive skills
Epilepsy & behavior, Vol.113, 107471
12/2020
PMID: 33142199
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Source: InCites
Abstract
Purpose
Long-term memory, which is critical for social and vocational functioning, is impaired in children with genetic generalized epilepsy (GGE). In this study, we examined the relationship between the temporal pattern of long-term forgetting for visual and verbal materials and executive skills in children with GGE.
Method
Thirty-two children, 17 with GGE and 25 typically developing age-matched controls completed standardized tests of short-term memory (recall after a 30-minute delay), executive skills, and experimental long-term memory tasks (one verbal and one visual) involving recall after one short (30-minute), and two long (1-day, 2-week) delays.
Results
On the long-term visual memory task, children with GGE performed comparably with typically developing children at a 30-minute delay (p = .298), although obtained lower object placement accuracy score, at 1 day (p = .039) and at 2 weeks (p = .022) relative to typically developing children. On the verbal task, the between-group difference was not significant at any delay. In children with GGE, poorer object placement accuracy at two weeks correlated with lower visuospatial short-term memory (r = −0.624, p = .005) and verbal working memory (r = −0.448, p = .041).
Conclusions
This study provided several novel findings. For the first time, accelerated long-term forgetting (ALF) was found in long-term visual memory in children with GGE, despite comparable learning and recall at 30 min. Study results indicated that deficits in long-term visual memory are present after one day, increase over time, and may relate to reduced executive skills. Our findings can be used to inform our understanding of the temporal trajectory of ALF and contribution of executive skills.
Details
- Title
- Accelerated long-term forgetting in children with genetic generalized epilepsy: The temporal trajectory and contribution of executive skills
- Creators
- Samantha Joplin - University of SydneyRichard Webster - Children's Hospital at WestmeadDeepak Gill - Children's Hospital at WestmeadBelinda Barton - Children's Hospital at WestmeadJohn A. Lawson - Sydney Children's HospitalAnna Mandalis - Sydney Children's HospitalMark Sabaz - Sydney Children's HospitalMichael Gascoigne - Australian College of Applied PsychologySuncica Lah - University of Sydney
- Publication Details
- Epilepsy & behavior, Vol.113, 107471
- Publisher
- Elsevier
- Number of pages
- 9
- Grant note
- 1115389 / National Health and Medical Research Council (NHMRC) postgraduate research scholarship, Canberra, ACT, Australia Lucy Firth Post-Graduate Research Scholarship University of Sydney
- Identifiers
- 991013093609402368
- Copyright
- Crown Copyright © 2020 Published by Elsevier Inc. All rights reserved.
- Academic Unit
- Faculty of Health
- Language
- English
- Resource Type
- Journal article