Journal article
A systematic review and meta-analysis of mindfulness-based stress reduction for arterial hypertension
Journal of Human Hypertension, Vol.37, pp.161-169
03/2023
PMID: 36216879
Metrics
14 Record Views
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites
Abstract
Arterial hypertension is a major public health issue. Non-pharmacological approaches like Mindfulness-Based Stress Reduction (MBSR) might be a promising addition to conventional therapy. This systematic review and meta-analysis aim to evaluate the effects of MBSR on systolic (SBP) and diastolic blood pressure (DBP) among individuals with prehypertension or hypertension. We searched Medline/PubMed, Scopus and the Cochrane Central Register of Controlled Trials (CENTRAL) for randomized controlled trials (RCTs) from their inception until August 1st 2021. RCTs were included that compared MBSR to any control intervention in participants with diagnosed prehypertension (120-139/80-89 mmHg) or hypertension (>= 140/>= 90 mmHg). Mean differences (MD) and 95% confidence intervals (CI) were calculated. Risk of Bias was assessed using the Cochrane tool. Seven RCTs with 429 participants were included. Very low quality of evidence was found for positive effects of MBSR on SBP (MD = -11.26 mmHg, 95%CI = -20.24 to -2.29, p = 0.01) but no evidence for effects on DBP levels (MD = -3.62 mmHg, 95%CI = -8.52 to 1.29, p = 0.15) compared to waitlist control. Compared to active control, very low quality of evidence was found for positive effects on DBP (MD = -5.51 mmHg, 95%CI = -10.93 to -0.09, p = 0.05) but no effects on SBP levels (MD = -4.33 mmHg, 95%CI = -12.04 to 3.38, p = 0.27). Overall, the studies showed a high degree of heterogeneity. The effects found were robust against selection, detection, and attrition bias. Only one RCT reported safety data. MBSR may be an option for lowering blood pressure in people with prehypertension to hypertension. More and larger high-quality studies are needed to substantiate our findings.
Details
- Title
- A systematic review and meta-analysis of mindfulness-based stress reduction for arterial hypertension
- Creators
- Christoph Geiger - University of Duisburg-EssenHolger Cramer - Universitätsklinikum TübingenGustav Dobos - University of Duisburg-EssenWiebke Kathrin Kohl-Heckl - University of Duisburg-Essen
- Publication Details
- Journal of Human Hypertension, Vol.37, pp.161-169
- Publisher
- Nature Publishing Group
- Number of pages
- 9
- Grant note
- This research received no specific funding. WKK-H was supported by a scholarship by the Karl and Veronica Carstens-Foundation, grant number KVC 0/113/2020; HC was supported by Erich Ruthenfußer Stiftung.
- Identifiers
- 991013055108902368
- Copyright
- © The Author(s), under exclusive licence to Springer Nature Limited 2022.
- Academic Unit
- National Centre for Naturopathic Medicine
- Language
- English
- Resource Type
- Journal article