Journal article
A poly-herbal blend (Herbagut®) on adults presenting with gastrointestinal complaints : a randomised, double-blind, placebo-controlled study
BMC Complementary and Alternative Medicine, Vol.18, pp.98-111
2018
Metrics
33 Record Views
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites
Abstract
<p>Background: To evaluate the efficacy and tolerability of a poly-herbal formulation, Herbagut, for the treatment of gastrointestinal symptoms and its effect on quality of life parameters in patients presenting with self-reported, unsatisfactory bowel habits. <br />Methods: This was a randomised, double-blind, placebo-controlled trial. Fifty adults with self-reported unsatisfactory bowel habits, primarily characterised by chronic constipation were randomly allocated to take Herbagut or a matching placebo for 28 days. Efficacy of gastrointestinal changes was measured by the completion of a patient daily diary evaluating changes in stool type (Bristol Stool Form Scale), ease of bowel movements, and feeling of complete evacuation; and the Gastrointestinal Symptom Rating Scale (GSRS). Changes in quality of life were also examined using the World Health Organization Quality of Life – abbreviated version (WHOQOL-BREF), and the Patient Assessment of Constipation-Quality of Life (PAC-QOL). <br />Results: All participants completed the 28-day trial with no adverse events reported. Compared to the placebo, weekly bowel movements increased over time (p < .001), as did self-reported, normal bowel motions (76% vs 4%; p < .001). Self-reported incomplete evacuation was also lower in the Herbagut group compared to placebo (24% vs 76%; p =Conclusion: Herbagut ingestion over a 28-day period resulted in improvements in several gastrointestinal symptoms and overall quality of life. Further investigation utilising larger sample sizes and diverse clinical and cultural populations are needed.</p>
Details
- Title
- A poly-herbal blend (Herbagut®) on adults presenting with gastrointestinal complaints : a randomised, double-blind, placebo-controlled study
- Creators
- Adrian L Lopresti - Murdoch UniversityHemant Gupta - Samvedna Hospital, IndiaStephen J Smith - Southern Cross University
- Publication Details
- BMC Complementary and Alternative Medicine, Vol.18, pp.98-111
- Identifiers
- 3627; 991012821315702368
- Academic Unit
- School of Health and Human Sciences
- Resource Type
- Journal article