Two novel diterpenoids were isolated from the bulbs of Fritillaria anhuiensis S. C. Chen and S. E. Yin. Compound 1 was the first diterpenoid containing a sulfonyl group isolated from nature. Compound 2 was a novel kaurane-type diterpenoid. Their structures were determined by extensive spectroscopic analysis (IR, MS, NMR, and X-ray diffraction). Compound 1 significantly attenuated nitric oxide (NO) production of a macrophage cell line of Raw 264.7 cells stimulated with IFN-γ.
Journal article
A novel sulfur-containing diterpenoid from Fritillaria anhuiensis
Tetrahedron Letters, Vol.50(28), pp.4185-4187
2009
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Abstract
Details
- Title
- A novel sulfur-containing diterpenoid from Fritillaria anhuiensis
- Creators
- Qing-Yao Shou - Shanghai University of Traditional Chinese MedicineQing Tan - Shanghai University of Traditional Chinese MedicineZheng-Wu Shen - Shanghai University of Traditional Chinese Medicine
- Publication Details
- Tetrahedron Letters, Vol.50(28), pp.4185-4187
- Identifiers
- 1195; 991012820778202368
- Academic Unit
- Southern Cross Plant Science
- Resource Type
- Journal article