A moderated mediation analysis of the association between smoking and suicide attempts among adolescents in 28 countries

Prince Peprah; Bernard Yeboah-Asiamah Asare; Reforce Okwei; Williams Agyemang-Duah; Joseph Osafo; Irene A Kretchy; Razak M Gyasi

doi:10.1038/s41598-023-32610-8

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A moderated mediation analysis of the association between smoking and suicide attempts among adolescents in 28 countries

Journal article

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Peer reviewed

A moderated mediation analysis of the association between smoking and suicide attempts among adolescents in 28 countries

Prince Peprah, Bernard Yeboah-Asiamah Asare, Reforce Okwei, Williams Agyemang-Duah, Joseph Osafo, Irene A Kretchy and Razak M Gyasi

Scientific reports, Vol.13, 5755

08/04/2023

DOI: https://doi.org/10.1038/s41598-023-32610-8

PMID: 37031212

Appears in Recent National Centre for Naturopathic Medicine Publications

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Abstract

Adolescent

Cigarette Smoking - epidemiology

Mediation Analysis

Risk Factors

Suicidal Ideation

Suicide, Attempted

Tobacco

Medical research

Psychology

Globally, evidence has shown that many adolescents are victims of substance use, mainly cigarette smoking, and it has been associated with suicidal ideation. However, the mechanisms underlying this association are poorly understood. This study examines whether truancy mediates and gender moderates the association of cigarette smoking with suicide attempts among adolescents in 28 countries. Data from the Global School-Based Student Health Survey were used. Hierarchical multiple logistic regression analyses were used to estimate the effect-modification of gender on cigarette smoking and suicide attempt. The mediating effect of truancy on the association between cigarette smoking and suicidal attempt was assessed using the generalized decomposition method. Cigarette smoking was associated with suicide attempts after adjusting for several confounding variables (aOR = 1.21; 95% CI = 1.09-1.33). The bootstrap results from the generalized decomposition analysis indicated that truancy partially mediated the association of cigarette smoking with a suicide attempt, contributing 21% of the total effect among in-school adolescents. Hierarchical regression analyses suggested that gender moderated the effect of cigarette smoking on suicidal attempts: female adolescents who smoked had 36% higher odds of suicidal attempts compared to male adolescents. The findings suggest possible pathways for designing and implementing interventions to address adolescents' cigarette smoking and truancy to prevent suicidal attempts.

Details

Title: A moderated mediation analysis of the association between smoking and suicide attempts among adolescents in 28 countries
Creators: Prince Peprah - University of New South Wales
Bernard Yeboah-Asiamah Asare - Curtin University
Reforce Okwei - Miami University
Williams Agyemang-Duah - Queen's University
Joseph Osafo - Centre for Suicide and Violence Research - CSVR, Accra, Ghana
Irene A Kretchy - University of Ghana
Razak M Gyasi - African Population and Health Research Center
Publication Details: Scientific reports, Vol.13, 5755
Publisher: Nature Publishing Group
Identifiers: 991013101602502368
Academic Unit: National Centre for Naturopathic Medicine
Language: English
Resource Type: Journal article

A moderated mediation analysis of the association between smoking and suicide attempts among adolescents in 28 countries

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UN Sustainable Development Goals (SDGs)

Abstract

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