The marine environment is a rich source of natural products that, as promising bioactive compounds, demonstrate environmentally friendly potential for application across
various industries [1,2]. These bioactive molecules may be used in environmental protection, supporting the transition to green sectors, and promoting the sustainable use of natural resources [3–6]. Proteomic studies play a crucial role in this process by analyzing the activity, stability, degradation, modification, and interactions of proteins, as well as their influence on metabolic pathways [7–9]. This approach also assesses variations in protein expression levels and the impact of differential gene expression on proteomic profiles [10,11]. Advances in proteomics, particularly through the integration of cutting-edge technologies such as mass spectrometry-based protein interactome studies, artificial intelligence (AI)-based approaches, and machine learning techniques are opening new frontiers in modern-day research explorations that were not possible in the past [12–14]. This rapid progress is especially vital in the medical field, where there is an urgent demand for novel and more effective therapeutic agents, disease biomarkers and addressing the needs of the aging population [15,16]. Moreover, proteomic insights are deepening our understanding of the bioactive potential of marine-derived bioproducts, paving the way for innovative applications in health and biotechnology
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Proteomic Studies for the Identification and Characterization of Marine Bioactive Molecules