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Make or break: psychotropic medications have off-label effects on neuromuscular performance
Editorial   Peer reviewed

Make or break: psychotropic medications have off-label effects on neuromuscular performance

Tyler T Henderson, Lucas B R Orssatto and Jacob R Thorstensen
British journal of sports medicine, Vol.60(12)
12/06/2026
PMID: 41850729

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Abstract

Despite their physical resilience and peak performances, athletes are at a significant risk of mental health conditions. Symptoms of anxiety and depression can affect 30%–40% of elite athletes,1–3 while up to 8% of all athletes are affected by the neurodevelopmental condition attention-deficit hyperactivity disorder (ADHD).4 Established interventions to manage and alleviate symptoms of mental health and neurodevelopmental conditions include psychological therapies, lifestyle and social interventions and pharmacological treatments.

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