Thesis
Genetic characterisation of cannabinoid composition in a diverse Cannabis germplasm collection
Southern Cross University, School of Environment, Science & Engineering
Doctor of Philosophy (PhD), Southern Cross University
2020
DOI:
https://doi.org/10.25918/thesis.78
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Abstract
Cannabis is a pharmaceutically valuable plant genus which produces a class of secondary metabolites, referred to as cannabinoids. The cannabinoid alkyl side-chain is a critical structural feature governing therapeutic activity. However, the genetic architecture responsible for variation in alkyl side-chain length is poorly understood. This thesis explores the genetic basis of cannabinoid alkyl side-chain homology using a series of experiments. Segregation analysis indicated that the alkyl side-chain chemotype was a digenic heritable trait, while advanced genomic analysis confirmed a known cannabinoid synthase locus as well as a series of candidate genomic regions for further functional characterisation.
Details
- Title
- Genetic characterisation of cannabinoid composition in a diverse Cannabis germplasm collection
- Creators
- Matthew Timothy Welling
- Contributors
- Graham King (Supervisor) - Southern Cross UniversityBen Liu (Supervisor) - Southern Cross University
- Awarding Institution
- Southern Cross University; Doctor of Philosophy (PhD)
- Theses
- Doctor of Philosophy (PhD), Southern Cross University
- Publisher
- Southern Cross University, School of Environment, Science & Engineering
- Number of pages
- xv, 173 pages
- Identifiers
- 991012893900502368
- Copyright
- © Matthew T. Welling 2019
- Academic Unit
- Faculty of Science and Engineering
- Resource Type
- Thesis