Conference proceeding
Airway bacterial interactions and impact on host immune responses
Recent advances in tonsils and mucosal barriers of the upper airways : proceedings of the 7th International Symposium , Vol.72, pp.116-120
Advances in Oto-Rhino-Laryngology
International Symposium on Tonsils and Mucosal Barriers of the Upper Airways, 7th (Asahikawa-shi, Japan, 07/07/2010 - 09/07/2010)
2011
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Abstract
The dynamic interactions of the major respiratory microbial pathogens are complex. An understanding of the impact on naturally acquired immune responses to respiratory polymicrobial commensal bacteria is slowly evolving. Maintaining a micro-floral balance and the host’s ability to respond to imbalances associated with disease is critical. Studies of acquired immune responses have found that both antibody and cellular immune responses are suppressed by the presence of multiple bacteria when compared with colonization by the single microbe. Microbes interact with the mucosal epithelium through a range of receptor-ligand interactions, including interactions with Toll-like receptors and adhesion molecules. Regulation of the inflammatory response associated with commensal colonization suggests a possible role for Treg cells in controlling the upper airway responses to bacterial microflora with both bacteria-bacteria and bacteria-host interactions affecting colonization and immune responses.
Details
- Title
- Airway bacterial interactions and impact on host immune responses
- Creators
- J Kyd - Central Queensland UniversityJ McGrath - Central Queensland UniversityA Krishnamurthy - Central Queensland UniversityJessica Browne - Central Queensland UniversityF Vahedi - Central Queensland University
- Publication Details
- Recent advances in tonsils and mucosal barriers of the upper airways : proceedings of the 7th International Symposium , Vol.72, pp.116-120
- Conference
- International Symposium on Tonsils and Mucosal Barriers of the Upper Airways, 7th (Asahikawa-shi, Japan, 07/07/2010 - 09/07/2010)
- Series
- Advances in Oto-Rhino-Laryngology
- Publisher
- Karger; Switzerland
- Number of pages
- 116-120
- Identifiers
- 3874; 991012822294902368
- Academic Unit
- Faculty of Health; Human Sciences; School of Health and Human Sciences
- Language
- English
- Resource Type
- Conference proceeding