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Current Threats to Biosecurity
Book chapter

Current Threats to Biosecurity

Chandini Raina MacIntyre, Damian Honeyman and David Heslop
Handbook of Emergency Response: A Human Factors and Systems Engineering Approach, Second Edition, pp.229-239
Environmental and Occupational Health Series, CRC Press, 2nd
2025

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Abstract

The acceleration of technologies for biological research is increasing the risk associated with laboratory accidents and deliberate releases. Advances in gain-of-function, synthetic biology, human genome editing, artificial intelligence, and an ever-expanding array of enhanced potential pandemic pathogens pose an increasing threat to biosafety and greater risk than ever of unnatural epidemics and pandemics. Despite these increased threats, public awareness of this research is low. This chapter proposes cross-disciplinary initiatives involving health sciences, law enforcement, intelligence, defense, emergency response, artificial intelligence, and community members to improve the regulation and oversight of evolving biological technology.

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